Objective: This study used super red dragon fruit peel and esh (Hylocereus costaricensis) which is high levels of anthocyanins and natural coloring agents that can be used as alternative materials for detecting plaque on surface of tooth. Material and Method: Were quasi-experimental design research with a post-test control group design. This research used 22 samples divided into four groups, application with aquadest, synthetic disclosing solutions, ethanol
extract of super red dragon fruit peel, and ethanol extract of super red dragon fruit esh. The assessment was carried out visually by looking at plaque index as measured by PHPI (Patient Hygiene Performance index) method. Data
were analyzed statistically with Kruskall Wallis test and Mann-Whitney test (p0.05). Conclusion: Ethanol extract of super red dragon fruit esh is more e ective as an ingredient for detecting plaque on the tooth surface because it has an acidic pH, which means the anthocyanin content can produce a red color.